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John Mann Selected Research

ridinilazole

1/2022Symmetric bis-benzimidazoles as DNA minor groove-binding agents with anti-tumour and antibacterial activity, and the evolution of the drug ridinilazole for the treatment of Clostridium difficile infections.
8/2015The discovery of a novel antibiotic for the treatment of Clostridium difficile infections: a story of an effective academic-industrial partnership.

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John Mann Research Topics

Disease

2Clostridium Infections
01/2022 - 08/2015
2Neoplasms (Cancer)
09/2007 - 01/2002
1Hypoxia (Hypoxemia)
11/2022
1Opiate Overdose
11/2022
1Heart Arrest (Cardiac Arrest)
11/2022
1Respiratory Insufficiency (Respiratory Failure)
11/2022
1COVID-19
10/2022
1Lymphopenia (Lymphocytopenia)
10/2022
1Down Syndrome Critical Region
11/2015
1Blindness (Hysterical Blindness)
12/2003
1Diabetic Retinopathy (Retinopathy, Diabetic)
12/2003

Drug/Important Bio-Agent (IBA)

2Pharmaceutical PreparationsIBA
10/2022 - 01/2022
2ridinilazoleIBA
01/2022 - 08/2015
1Fentanyl (Sublimaze)FDA LinkGeneric
11/2022
1carfentanil (carfentanyl)IBA
11/2022
1Opioid Analgesics (Opioids)IBA
11/2022
1Naloxone (Narcan)FDA LinkGeneric
11/2022
1Narcotic Antagonists (Opioid Antagonists)IBA
11/2022
1mu Opioid Receptors (mu Opioid Receptor)IBA
11/2022
1CytokinesIBA
10/2022
1triphosphoric acid (triphosphate)IBA
10/2022
1ProdrugsIBA
10/2022
1NucleosidesIBA
10/2022
1remdesivirIBA
10/2022
1DNA (Deoxyribonucleic Acid)IBA
01/2022
1BenzimidazolesIBA
01/2022
1Phosphotransferases (Kinase)IBA
11/2015
1Tyrosine (L-Tyrosine)FDA Link
11/2015
1Anti-Bacterial Agents (Antibiotics)IBA
08/2015
1Monoamine Oxidase (MAO)IBA
09/2007
1Angiogenesis InhibitorsIBA
12/2003

Therapy/Procedure

1Induced Heart Arrest (Cardioplegia)
11/2022
1Therapeutics
10/2022
1Drug Therapy (Chemotherapy)
01/2002